Job Description

Rezolute is a late-stage rare disease company focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Our antibody therapy, RZ358 (ersodetug), is designed to treat all forms of HI and has shown substantial benefit in clinical trials and real-world use for the treatment of congenital hyperinsulinism (cHI) and tumor hyperinsulinism (tHI)

Position Summary

We are seeking a strategic and execution-oriented Vice President of Marketing to lead all marketing functions for our emerging biopharmaceutical company, including the launch of our lead rare disease product and the commercial planning for our broader pipeline. As a core member of the executive team, this leader will develop and drive integrated marketing strategies that position the company for success in rare disease markets. The ideal candidate combines deep launch experience, a strong patient- and physician-centric mindset, and the ability to scale marketing capabilities as the company grows.

Key Responsibilities

• Lead the U.S. and/or global go-to-market strategy for the launch of the company's lead rare disease asset.
• Define and evolve brand positioning, messaging, and differentiation for HCP, patient, and payer audiences.
• Develop branded and unbranded campaigns, disease awareness initiatives, and promotional materials.
• Coordinate cross-functional alignment with Sales, Market Access, Medical Affairs, Regulatory, and Patient Advocacy to ensure launch success.

• Partner with R&D, Business Development, and Executive Leadership to provide commercial input into pipeline asset development and prioritization.
• Lead early-stage commercial assessments , including market opportunity analyses, competitive landscapes, and unmet need evaluations for pipeline indications.
• Develop target product profiles (TPPs) , commercial forecasts, and lifecycle management strategies for future assets.
• Build early brand strategies and pre-commercialization plans to ensure future readiness.

• Build and lead a high-performing marketing team across HCP, patient, and digital marketing disciplines.
• Manage agencies, vendors, and internal resources to ensure efficient and impactful execution.
• Define key performance indicators and lead marketing performance analysis in partnership with Commercial Operations.
• Foster a high-accountability, mission-driven culture aligned with company values and patient focus.

• Oversee market research and insights to inform strategy, understand stakeholder needs, and adapt to market dynamics.
• Engage with key external stakeholders including KOLs, treatment centers, advocacy organizations, and payer influencers.
• Ensure strong feedback loops with the field team to align messaging and identify barriers to adoption.

• Lead the development of an integrated digital marketing strategy, including social media, CRM, HCP and patient websites, and omni-channel campaigns.
• Leverage data analytics and digital platforms to optimize outreach and measure engagement across channels.

• Ensure all marketing and promotional activities are compliant with regulatory, legal, and corporate policies.
• Develop and manage marketing budgets and timelines, ensuring efficient resource allocation and spend.

• 15+ years of progressive experience in pharmaceutical/biotech marketing, with at least 5 years in a commercial leadership role.
• Proven track record launching specialty or rare disease products in the U.S. markets.
• Demonstrated experience with pipeline planning and early commercial strategy development.
• Deep understanding of the rare disease ecosystem including patient journeys, diagnostics, market access, and advocacy.
• Strong leadership and team-building capabilities in a small or scaling company environment.
• Exceptional collaboration, executive communication, and strategic thinking skills.
• Bachelor’s degree required; MBA or advanced degree preferred.

• Experience in both pre-commercial and commercial-stage biotech organizations.
• Entrepreneurial mindset and comfort operating in a fast-paced, evolving environment.
• Ability to work in a lean organization with a hands-on, roll-up-your-sleeves style.
• Passion for improving the lives of patients with rare and underserved diseases.

Rezolute (RZLT) currently anticipates the base salary for the Vice President of Marketing role could range from $000,000 to $000,000 and will depend, in part, on the successful candidate’s geographical location and their qualifications for the role, including education and experience. This position will also be eligible for an annual performance bonus in accordance with the terms of the applicable plan (depending, in part, on company and individual performance and at the Company’s discretion on an individual basis). The compensation described above is subject to change and could be higher or lower than the range described based on current market survey data and the qualifications, education, experience and geographical location of the selected candidate.

Qualifying employees are eligible to participate in benefit programs such as:

·Health Insurance (Medical / Dental / Vision)

·Disability, Life & Long-Term Care Insurance

·Holiday Pay

·Tracking Free Vacation Program

·401(k) Plan Match

·Educational Assistance Benefit

·Fitness Center Reimbursement

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.

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